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巨龙生物4-羟基异亮氨酸研发取得突破进展
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巨龙生物4-羟基异亮氨酸研发取得突破进展
摘要:巨龙生物成功研发获得了4-羟基异亮氨酸(4-HIL)制备新工艺,并同时表现出扩大L-色氨酸业务的意愿,但同时也意味着巨龙生物需承担着色氨酸价格低迷的风险。2016年3月7日,河南巨龙生物工程股份有限公司(巨龙生物)发布公告称,公司成功研发获得了4-羟基异亮氨酸(4-HIL)制备新工艺,该工艺利用生物发酵法制备4-HIL,通过宿主中 脱氧酮糖酸和磷酸戊糖 氧化 支链中的 酶 使其失活,大幅度提高L-异亮氨酸的转化率,可实现高纯度4-HIL的工业化生产。而利用生物发酵法制备4-HIL属于世界首...
Amino Acids China E-News 201603 (Chinese version)
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